Job Opportunities
M.A.G.I.C. Clinic (Metabolics and Genetics in Canada) is a thriving community-based clinic committed to providing the most advanced care for patients with genetic or metabolic diseases. Our approach focuses on high quality personalized services for children and adults for the diagnosis and management of inborn errors of metabolism, clinical genetics, and prenatal care. We provide insured services for the public in our scope of practice and collaborate with accredited institutions like Discovery DNA, and other providers, for private genomic services. Our Genetic Treatments and Clinic Trials Unit (CTU), accredited as a Biosafety Level II facility, is integrated with our pharmacy to provide an autonomous environment for working with gene therapy trials, intrathecal therapies, intravenous and oral treatments. We strive to offer a collaborative environment where specialists can grow professionally while making a difference in the lives of patients and families. Many of our patients are on novel therapies and we perform more than 150 diagnostic and therapeutic lumbar punctures per year, have more than 20 active clinical trials, perform diagnostic needle muscle biopsies and have a busy practice with more than 4,000 patient visits per year. Join us as we move into our new state-of-the art 8,000 square foot Clinic and CTU later this year.
Position: Clinical and Metabolic Geneticist
Location: 971 – 64 Avenue NE, Ste 215, Calgary, Alberta, Canada
Employment Type: Fee for Service, Physician
Dates Application is Open: 1 May 2025 – 31 May 2025
Job Opportunities
Position: Clinical and Metabolic Geneticist
Location: 971 – 64 Avenue NE, Ste 215, Calgary, Alberta, Canada
Employment Type: Fee for Service, Physician
Dates Application is Open: 1 May 2025 – 31 May 2025
M.A.G.I.C. Clinic (Metabolics and Genetics in Canada) is a thriving community-based clinic committed to providing the most advanced care for patients with genetic or metabolic diseases. Our approach focuses on high quality personalized services for children and adults for the diagnosis and management of inborn errors of metabolism, clinical genetics, and prenatal care. We provide insured services for the public in our scope of practice and collaborate with accredited institutions like Discovery DNA, and other providers, for private genomic services. Our Genetic Treatments and Clinic Trials Unit (CTU), accredited as a Biosafety Level II facility, is integrated with our pharmacy to provide an autonomous environment for working with gene therapy trials, intrathecal therapies, intravenous and oral treatments. We strive to offer a collaborative environment where specialists can grow professionally while making a difference in the lives of patients and families. Many of our patients are on novel therapies and we perform more than 150 diagnostic and therapeutic lumbar punctures per year, have more than 20 active clinical trials, perform diagnostic needle muscle biopsies and have a busy practice with more than 4,000 patient visits per year. Join us as we move into our new state-of-the art 8,000 square foot Clinic and CTU later this year.
Job Description
We are seeking a qualified and experienced Clinical and Metabolic Geneticist (or equivalent) to join our team. The successful candidate will play a pivotal role in diagnosing and managing genetic and metabolic conditions, counseling patients and families, providing novel therapies and contributing to multidisciplinary care. This role offers an excellent opportunity to work with cutting-edge genomic technologies, participate in clinical research, and collaborate with an expert team of healthcare professionals. We have collaborations that allow the Geneticist to explore the data on whole exome and whole genome sequencing, offer non-invasive prenatal screening (NIPS) in pregnancy, access to metabolomic and transcriptomic technologies, mitochondrial DNA long read sequencing and many other techniques to help you make that diagnosis in your patient.
Key Responsibilities
- Evaluate and manage patients with genetic disorders or at risk for inherited conditions.
- Conduct detailed patient histories, physical examinations, and genetic testing as needed.
- Interpret genetic test results and communicate findings with patients, families, and referring physicians.
- Provide genetic counseling to patients and families regarding hereditary conditions, test results, and potential treatments.
- Work closely with a multidisciplinary team to coordinate patient care.
- Participate in teaching and training of medical residents, genetic counseling students, and other healthcare staff.
- Contribute to clinical research projects and stay current with advancements in genetics.
- Evaluate and manage patients with genetic disorders or at risk for inherited conditions.
- Conduct detailed patient histories, physical examinations, and genetic testing as needed.
- Interpret genetic test results and communicate findings with patients, families, and referring physicians.
- Provide genetic counseling to patients and families regarding hereditary conditions, test results, and potential treatments.
- Work closely with a multidisciplinary team to coordinate patient care.
- Participate in teaching and training of medical residents, genetic counseling students, and other healthcare staff.
- Contribute to clinical research projects and stay current with advancements in genetics.
- Work in a collaborative environment with nurse clinicians, genetic counsellors, research co-ordinators, physiotherapists, lab scientists and administrators.
Medical Doctor (MD) degree or equivalent and either have or be eligible for permanent licensing through the College of Physicians and Surgeons of Alberta (CPSA) AND any of the following specialist certifications
- Specialist certification through the Royal College of Physicians and Surgeons of Canada in Medical Genetics or
- Specialist certification through the Royal College of Physicians and Surgeons of Canada in Pediatrics or Internal Medicine with additional certifications in a clinical specialty through the Canadian College of Medical Geneticists
- Certification through the College of Family Physicians of Canada with additional certifications in a clinical specialty through the Canadian College of Medical Geneticists
- Proven experience in a clinical and metabolic genetics setting.
- Proficiency in English.
- Excellent interpersonal and communication skills for patient interactions and teamwork.
- Experience with genomic technologies such as next-generation sequencing and ability to assess variants in a diagnostic setting (we are not requiring you to run the test but be familiar with how variant analysis is interpreted).
- Prior involvement in clinical research.
- Ability to perform or train in performing lumbar puncture in sedated and non-sedated patients of all ages.
- Ability to perform or train in performing diagnostic needle muscle biopsies and skin biopsies.
- Competency in or be willing to train to be a principal investigator or co-investigator in clinical trials, gene therapies and other novel therapies.
- Excellent interpersonal and communication skills for patient interactions and teamwork.
- Remuneration for clinical services is based on fee-for-service billing according to medical specialty and appropriate fee schedules minus a deduction for overhead.
- Remuneration for research services is based on fee-for-service billing according to specific research study fee schedule
- Work schedule is flexible. Typical service hours for M.A.G.I.C. Clinic are between 9 am – 3:30 pm on weekdays and the clinic does not open on the weekends with some exceptions. After hours coverage is off-site and remuneration is based on fee-for-service billing.
- Start date is negotiable but is anticipated 1 July 2025.
- A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age With Fabry Disease.
- Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment.
- ST920 LTE. Fabry Gene Therapy. Long-Term Follow-up of Subjects Who Were Treated with ST-920.
- A Gene Therapy Study in Patients With Gaucher Disease Type 1.
- A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age.
- GTX-102. Long-term Extension of GTX-102 in Angelman Syndrome.
- Long Term Follow Up to Evaluate DTX301 in Adults With Late-Onset OTC Deficiency.
- PTC923-004. A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria.
- Rare Disease Diagnosis – Phase 1b (Part 1) – a collaboration between Alberta Health Services, Saventic Health Canada and MAGIC Clinic.
- ALXN1850-301. Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa.
- ALXN1850-305. Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP.
- A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (pegvaliase) During Pregnancy and Breastfeeding.
- Study to Assess the Safety, Tolerability, PK and PD of ABX1100.
- Long term use of Intrathecal Adrabetadex in patients with Niemann Pick C.
- BMN111-211. A Phase 2, Randomized, Human Growth Hormone-Controlled, Multicenter, Basket Study of Vosoritide in Children with Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome with an Inadequate Response to Human Growth Hormone.
- Canadian Fabry Disease Initiative National Registry.
- Gaucher Registry.
- Fabry Registry.
- Pompe Registry.
- Follow-Me Registry. A PROSPECTIVE, OBSERVATIONAL REGISTRY OF PATIENTS WITH FABRY DISEASE Protocol # AT1001-030.
- Fabry cardiomyopathy: Identification of Early myocardial Structural and Tissue Abnormalities using multiparametric MRI.
- Verified Interest to Participate in Research.
- Fabry HCM. Screening for Fabry Cardiomyopathy using Magnetic Resonance Imaging (CMR).
- Lyso-Care. Long Term Observational Study for Patients with Lysosomal Diseases after Gene Therapy (Lyso-Care).
- Patient self-report questionnaire for Ehlers-Danlos Syndrome.
- JNT-517 in patients with Phenylketonuria.
- AZA-001-5B3-01 & AZA-001-5A3-01 Phase III Studies in Lysosomal Storage Diseases. 18 Month Double-Blind, Randomised, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-Infantile and Juvenile Onset Forms of GM1 Gangliosidosis or GM2 Gangliosidosis (Tay-Sachs and Sandhoff Disease.
- Alberta Health Data Assets: Rare Disease Real World Evidence for Regulatory Use.

How To Apply:
Interested candidates should submit a CV, cover letter, and three professional references to aneal.khan@discoverydna.ca. Please include “Clinical and Metabolic Geneticist Application: M.A.G.I.C. Clinic” in the subject line.
We thank all applicants for their interest. Only those selected for an interview will be contacted.
+1 (587) 885-3158