Dr. Khan graduated from the University of Toronto with a Master of Science in Nutrition. He completed his MD degree at Queen’s University in Kingston, Ontario, and Pediatric specialty training followed by Medical Genetics training at Rush Medical College in Chicago and the Hospital for Sick Children in Toronto. He has worked at the Hospital for Sick Children, University Health Network, McMaster Children’s Hospital, and Alberta Children’s Hospital.

He was the first physician in the world to treat Fabry disease and Gaucher disease using Gene Therapy, the first in Canada to use Liver Cell Transplant and Gene Therapy to treat Urea Cycle Diseases and is experienced in using research drugs injected directly into the spine.

Dr. Khan has extensive experience in diagnosing and treating mitochondrial diseases and published the largest clinical trial in Canada, called MITO-FIND, focusing on using DNA sequencing methods to diagnose mitochondrial disease.  After having performed hundreds of muscle biopsies on children and adults, he worked with his team to develop a mitochondrial DNA sequencing method that can make a diagnosis from a cheek swab using Nanopore sequencing without the need to do a muscle biopsy in the majority of cases.