Welcome to M.A.G.I.C. Clinic LTD!
M.A.G.I.C. stands for Metabolics And Genetics In Calgary
We focus on caring for children and adults with rare diseases caused by changes in their genes. There are more than 2,000 known diseases that lead to either metabolic diseases or genetic syndromes. Often, the problems can include neurologic diseases with features like seizures, developmental and growth problems, or heart, liver or muscle diseases where someone’s health continues to get worse and no explanation can be found through standard testing through your doctor.
Examples of METABOLIC DISEASES include things like mitochondrial diseases, leukodystrophies, glycogen storage diseases, fatty acid oxidation defects, lysosomal storage diseases and certain metabolic bone diseases. Examples of GENETIC SYNDROMES include things like Fragile X syndrome, Angelman syndrome, Rett syndrome and many other such conditions.
We use innovative approaches to help find a diagnosis faster and our approach to treatment uses knowledge to improve health but we also deal with specialized medicines to treat rare diseases as well as many research studies.
Let’s get in touch!
Location: 215-971 64 Ave NE, Calgary, Alberta, Canada, T2E 7Z4
Call: +1 (587) 885-3158 (Note: Our phone line is experiencing disruptions – please call 403-338-9669 (business hours),
or call your local emergency number/visit your nearest emergency department (in emergencies)
Fax: +1 (866) 566-7683
Zamplo is an App that lets you monitor your symptoms, response to therapy, keep track of your medications, make notes and keep track of your medical records all from your smartphone. It’s free and signing up to the study will open full functionality of the App as part of our research trial.
WHO WE ARE
New Research Studies
A FOLLOW-UP STUDY OF SUBJECTS WITH TYPE 1 GAUCHER DISEASE WHO PREVIOUSLY RECEIVED AVR-RD-02 GENE THERAPY.
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A DOUBLE-BLIND, PLACEBO-CONTROLLED, STUDY TO EVALUATE THE EFFICACY AND SAFETY OF 24 WEEKS TREATMENT WITH REN001 IN PATIENTS WITH PRIMARY MITOCHONDRIAL MYOPATHY (PMM)
status: site selected, ethics application being prepared
ACTIVE RESEARCH STUDIES: CONTACT US IF YOU ARE INTERESTED IN ENROLLING
Gene Therapy Trials:
AVRD-RD-01-201: Gene Therapy for Fabry disease – RECRUITING.
AVRD-RD-02-201: Gene Therapy for Gaucher disease – RECRUITING
301OTC02: OTC Gene Therapy Long Term Follow Up Study – RECRUITMENT COMPLETED
FACTS: Phase 1 Gene Therapy for Fabry disease – RECRUITMENT COMPLETED
MODIFY Open Label Extension – Open to only those patients that completed the main MODIFY study
SHP 609-203: Intrathecal Elaprase in patients with Hunter syndrome – RECRUITMENT COMPLETED.
EFC13738 / ELIKIDS: Eliglustat in Children with type I Gaucher disease – RECRUITING
ATB200-04: An Open-Label study of Pharmocokinetics, Safety, Efficacy and Pharmacodynamics of ATB200/AT2221 in Pediatrics Subjects Aged 12 to < 18 years with Late-Onset Pompe Disease – RECRUITING
ATB200-07 OLE: Late Onset Pompe disease – RECRUITMENT COMPLETED
Gene Sequencing Studies:
EXOME SCREENING FOR CAUSES OF HYPERTROPHIC CARDIOMYOPATHY LIKE FABRY DISEASE – RECRUITING
Registry and Natural History Studies:
CFDI-NR (Canadian Fabry Disease Initiative Registry) – RECRUITING
FABRY REGISTRY – RECRUITING
GAUCHER DISEASE REGISTRY – RECRUITING
MPS1 REGISTRY – RECRUITING
POMPE DISEASE REGISTRY – RECRUITING
Dietary Patterns and Supplement Use in Mitochondrial Disease – RECRUITING
Fabry Biomarker Switch ERT STUDY
Oudit Fabry Biomarker Study
Ask the Mito Doc: https://www.youtube.com/watch?v=IZ-eQ84Mxx0
Liver Cell Transplant: https://www.youtube.com/watch?v=lCAdr05J0AI
Gene Therapy General Information: https://vimeo.com/513277182
Healthy City Talks: https://www.youtube.com/watch?v=Tto6YNwTs7U